Hey, I just got back from a weekend trip with my girlfriend to santa barbara from la, its about 200 mi, round trip, but we did a lot of riding up there around wine country, and took the long way thru mailbu so overall it was 340 mi round trip. We were pretty exhausted, both being a little above 6 feet tall. All stock on the bike too, 2011. Mostly though it was lower back that ached. I've done 300 miles in one day before alone, and it didn't exhaust me as much as this trip. I ordered the Corbin seats, both front and rear, which come in like 3 more weeks, hopefully this will do the trick, because I would like that not to be the last time she wants to go for the long of a ride up on that tiny rear seat. But it helped that each time we got gas we just relaxed for about 15 mins, made a huge difference. Biker padded pants seems like a good idea too, on the way back we put a sweater under her bum, which helped a lot too, impromptu plan b =) We both knocked out the moment we got home though. But today, I feel great, like nothing happened. I even took it the 30 miles to work this morning, feel great! Enjoy your trip, the Z is made for these excursions. A windscreen isnt a bad idea either, the wind can be brutal!